Chemotherapy, surgery and radiotherapy are USFDA-approved treatments that have long been used as primary and secondary treatments for cancer. However, when cancer recurs in the future, or when these primary and secondary treatments are unable to reduce or kill cancer, then doctors and patients may opt for other types of treatments including immunotherapy and also...
Compassionate drug use means making a new drug, which is still in clinical trials, available to treat a seriously ill patient when no other treatments are available. This is different from the use of drugs as part of a clinical trial, which is called Investigational Use. Such drugs are only available to patients who are...
The pre-evaluation phase takes up to 4 weeks. Once completed, blood collection will take 1 day. The process of manufacturing the CAR T-Cells will then take up to 4 weeks, after which you will have to undergo pre-conditioning chemo, which can last up to 4 days (2 to 14 days before CAR T-Cell infusion. After...
Cytopenia – Cytopenia occurs when one or more of the blood cell types are lower than it should be. Blood consists of red blood cells which carry oxygen and nutrients around the body, and white blood cells which fight infection. B-Cell Aplasia – B-Cell aplasia occurs when anti-CD19 CAR T-Cells kill normal B lymphocytes that...
Patients must meet the following criteria to be eligible for CAR T-Cell Immunotherapy: Patient is well enough to receive CAR T-Cell Immunotherapy. Tumour has expressed the appropriate marker, e.g. CD19. An Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1. Absence of disease complications or chemo-toxicity; such as, infection, active GVHD, hyperleucocytosis, severe...
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