Live For More
With CAR T-Cell
Immunotherapy

A cancer diagnosis is life changing, and when your body doesn’t respond well to conventional treatment options, losing sight of what you’re fighting for can be easy. CAR T-Cell Immunotherapy provides a chance to fight back, offering a reminder of why you live by empowering you to rewrite your cancer story.

An Opportunity For
Life Beyond Cancer

It can be easy to lose track of what you’re fighting for. Chemotherapy, radiation and surgery are no longer the
endgame. Through CAR T-Cell immunotherapy, we believe
that there is life beyond cancer.

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Live For More
With CAR T-Cell
Immunotherapy

A cancer diagnosis is life changing, and when your body doesn’t respond well to conventional treatment options, losing sight of what you’re fighting for can be easy. CAR T-Cell Immunotherapy provides a chance to fight back, offering a reminder of why you live by empowering you to rewrite your cancer story.

An Opportunity For Life
Beyond Cancer

It can be easy to lose track of what you’re fighting for. Chemotherapy, radiation and surgery are no longer the endgame. Through CAR T-Cell immunotherapy, we believe
that there is life beyond cancer.

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THE TREATMENT

With CAR T-Cell Immunotherapy,
The Power Comes From Within

CAR T-Cell Immunotherapy boosts the immune system’s ability to identify and combat specific cancers by engineering T-Cells in the immune system to target and eradicate specific cancer cells in the body.

Immunotherapy Is Being Hailed As
The 5th Pillar Of Cancer Treatment

Surgery, radiotherapy, chemotherapy and precision therapy make up the four established pillars of cancer treatment. Immunotherapy is now firmly being hailed as the 5th pillar, offering patients a renewed hope.

Source: National Institute of Allergy and Infectious Diseases/NIH

CANCER CARE
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Surgery

ANCIENT TIMES – PRESENT

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Radiotherapy

1890s – PRESENT

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Traditional
Chemotherapy

1940s – PRESENT

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Precision
Therapy

1998 – PRESENT

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Immunotherapy

1997 – PRESENT

THE DIFFERENCE

Chemotherapy
VS Immunotherapy

While chemotherapy and immunotherapy both aim to rid the human body of cancerous cells, the way two treatments work differ vastly. We’ve laid out the differences to encourage informed decisions for everyone.

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THE DIFFERENCE

Chemotherapy
VS Immunotherapy

While chemotherapy and immunotherapy both aim to rid the human body of cancerous cells, the way two treatments work differ vastly. We’ve laid out the differences to encourage informed decisions for everyone.

FAQ

Have Questions About The Process?
We’ve Got You Covered

CAR T-Cell Homepage FAQ

  • Who Is Eligible For CAR T-Cell Immunotherapy?

    Patients must meet the following criteria to be eligible for CAR T-Cell Immunotherapy:
    • Patient is well enough to receive CAR T-Cell Immunotherapy.
    • Tumour has expressed the appropriate marker, e.g. CD19.
    • An Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
    • Absence of disease complications or chemo-toxicity; such as, infection, active GVHD, hyperleucocytosis, severe extra medullary disease.
    • Last dose of chemotherapy and/or steroid is at least 2 weeks prior; when in doubt, a T-Cell activation test will be performed.
    • Patient’s tumour burden is as low as possible. In patients with uncontrolled or accelerating tumour burden, induction chemotherapy should be performed first (apheresis should be done prior to commencing the chemotherapy).

  • What Are The Possible Side Effects Of CAR T-Cell Immunotherapy?

    • Cytopenia – Cytopenia occurs when one or more of the blood cell types are lower than it should be. Blood consists of red blood cells which carry oxygen and nutrients around the body, and white blood cells which fight infection.
    • B-Cell Aplasia – B-Cell aplasia occurs when anti-CD19 CAR T-Cells kill normal B lymphocytes that express CD19. These patients are typically at high risk of developing infections, because of their hypogammaglobulinemia. However, this can be treated with intravenous immunoglobulin (IVIG) replacement therapy.
    • Cytokine Release Syndrome (CRS) – Potentially life-threatening condition that results from the pathologic over-activation of T-Cells. It is an acute systemic inflammatory syndrome characterised by fever and multiple organ dysfunction.
    • Neurotoxicity – Damage to the brain or peripheral nervous system caused by exposure to natural or man-made toxic substances. These toxins can alter the activity of the nervous system in ways that can disrupt or kill nerves.

  • What If The Requirements For CAR T-Cell Immunotherapy Are Not Met?

    • T-Cell Cryopreservation Option
    If any of the above requirements are not met for the patient to be eligible to undergo the CAR T-Cell immunotherapy for the time being, there is an option for the patient to freeze their T- Cells for future use once treatment can proceed.

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    For a more in-depth understanding on
    CAR T-Cell Immunotherapy, we’ve
    prepared a brochure that provides you
    with the information you need.

    For a more in-depth understanding on CAR T-Cell Immunotherapy, we’ve prepared a brochure that provides you with the information you need.

    Have Any Questions About CAR T-Cell
    Immunotherapy That Isn’t Listed On Our FAQ Page?
    Reach Out To Us And We’ll Get In Touch.

    COMPANY

    Sign up for you and your loved ones to receive the latest news and updates about CAR T-Cell Immunotherapy.

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      Copyright © 2021 Malaysian Genomics Resource Centre Berhad (652790-V). All Rights Reserved.

      Copyright © 2021 Malaysian Genomics Resource Centre Berhad (652790-V). All Rights Reserved.